The Australian Immunisation Handbook (Handbook) is the national clinical guideline advising health professionals on the safest and most effective use of vaccines. The Australian Technical and Advisory Group on Immunisation (ATAGI) develops all clinical advice and recommendations in the Handbook, which is endorsed by the National Health and Medical Research Council (NHMRC).

NCIRS plays a major role in, and leads the development of, the Handbook: 

  • We monitor and review changes in the immunisation landscape, from vaccine registrations to new scientific evidence, which are relevant to formulating and updating recommendations in the Handbook.

  • We synthesise, interpret and translate the best available scientific evidence to help develop evidence-based clinical recommendations on the use of vaccines in the Handbook. This includes undertaking literature searches, critical appraisal of literature and preparation of evidence summaries. 

  • We review and update all Handbook chapters in collaboration with the lead ATAGI member responsible for the chapter, together with external experts as required.

  • We develop a number of NCIRS resources for immunisation providers that support their understanding of the content, especially recommendations, of the Handbook.

Last updated December 2018